The difference in principle makes the bottom exhaust steam sterilization eliminated by the pulsating vacuum steam sterilization

Author: Jules Hsu 1 March 2025 Catalog: Sterilization methods

The principle of bottom exhaust pressure steam sterilization:

Using the principle of different specific gravity of steam and cold air for replacement, the steam in the sterilizer will discharge the cold air from the bottom exhaust hole from top to bottom, and replace it with saturated steam. However, the steam will squeeze the cold air to both sides during the descent process, and a large amount of cold air will be squeezed to the ends of both sides of the channel and compressed into cold air masses, thus forming cold spots, causing sterilization failure within this range.

The principle of pulsating pre-vacuum steam sterilization:

The cold air is first removed by mechanical vacuuming. In order to avoid residual cold air, steam will be used to break the vacuum. After reaching a certain pressure, vacuum is then drawn again, and the process is repeated several times, so as to ensure that more than 99.99% of the cold air in the sterilizer and the items is discharged, avoiding the existence of cold spots and ensuring the reliability of sterilization. In addition, the vacuum state allows steam to quickly penetrate the inside of the items for sterilization. Several cycles of vacuuming and steam replenishment make the pressure curve pulsating, which is the origin of the name of the pulsating vacuum sterilizer.

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